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Knockout of ISCA1 causes early embryonic death in rats

BACKGROUND: Iron‐sulfur cluster assembly 1 (ISCA1) is an iron‐sulfur (Fe/S) carrier protein that accepts Fe/S from a scaffold protein and transfers it to target proteins including the mitochondrial Fe/S containing proteins. ISCA1 is also the newly identified causal gene for multiple mitochondrial dy...

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Detalles Bibliográficos
Autores principales: Yang, Xinlan, Lu, Dan, Zhang, Xu, Chen, Wei, Gao, Shan, Dong, Wei, Ma, Yuanwu, Zhang, Lianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431120/
https://www.ncbi.nlm.nih.gov/pubmed/31016283
http://dx.doi.org/10.1002/ame2.12059