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NF-κB activation is a turn on for vaccinia virus phosphoprotein A49 to turn off NF-κB activation
Vaccinia virus protein A49 inhibits NF-κB activation by molecular mimicry and has a motif near the N terminus that is conserved in IκBα, β-catenin, HIV Vpu, and some other proteins. This motif contains two serines, and for IκBα and β-catenin, phosphorylation of these serines enables recognition by t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431142/ https://www.ncbi.nlm.nih.gov/pubmed/30819886 http://dx.doi.org/10.1073/pnas.1813504116 |