Cargando…

NF-κB activation is a turn on for vaccinia virus phosphoprotein A49 to turn off NF-κB activation

Vaccinia virus protein A49 inhibits NF-κB activation by molecular mimicry and has a motif near the N terminus that is conserved in IκBα, β-catenin, HIV Vpu, and some other proteins. This motif contains two serines, and for IκBα and β-catenin, phosphorylation of these serines enables recognition by t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Neidel, Sarah, Ren, Hongwei, Torres, Alice A., Smith, Geoffrey L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2019
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431142/ https://www.ncbi.nlm.nih.gov/pubmed/30819886 http://dx.doi.org/10.1073/pnas.1813504116

Ejemplares similares

Vaccinia virus protein C4 inhibits NF-κB activation and promotes virus virulence
por: Ember, Stuart W. J., et al.
Publicado: (2012)

Life, death, and autophagy in cancer: NF-κB turns up everywhere
por: Verzella, Daniela, et al.
Publicado: (2020)

Vaccinia virus BTB-Kelch proteins C2 and F3 inhibit NF-κB activation
por: Zhang, Rui-Yao, et al.
Publicado: (2022)

Leaky scanning translation generates a second A49 protein that contributes to vaccinia virus virulence
por: Neidel, Sarah, et al.
Publicado: (2020)

Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the pro-apoptotic NF-κB
por: Buontempo, Francesca, et al.
Publicado: (2015)

The oncogenic Golgi phosphoprotein 3 like overexpression is associated with cisplatin resistance in ovarian carcinoma and activating the NF-κB signaling pathway
por: He, Shanyang, et al.
Publicado: (2017)

HTLV-1 activates YAP via NF-κB/p65 to promote oncogenesis
por: Zhao, Tiejun, et al.
Publicado: (2022)

Vaccinia Virus Inhibits NF-κB-Dependent Gene Expression Downstream of p65 Translocation
por: Sumner, Rebecca P., et al.
Publicado: (2014)

Role of Monoubiquitylation on the Control of IκBα Degradation and NF-κB Activity
por: Da Silva-Ferrada, Elisa, et al.
Publicado: (2011)

Inhibition of Apoptosis and NF-κB Activation by Vaccinia Protein N1 Occur via Distinct Binding Surfaces and Make Different Contributions to Virulence
por: Maluquer de Motes, Carlos, et al.
Publicado: (2011)

Human primed ILCPs support endothelial activation through NF-κB signaling
por: Vanoni, Giulia, et al.
Publicado: (2021)

Single TNFα trimers mediating NF-κB activation: stochastic robustness of NF-κB signaling
por: Lipniacki, Tomasz, et al.
Publicado: (2007)

Human immunodeficiency virus-1 Tat activates NF-κB via physical interaction with IκB-α and p65
por: Fiume, Giuseppe, et al.
Publicado: (2012)

Vaccinia Virus BBK E3 Ligase Adaptor A55 Targets Importin-Dependent NF-κB Activation and Inhibits CD8(+) T-Cell Memory
por: Pallett, Mitchell A., et al.
Publicado: (2019)

NF-κB and Disease
por: Poma, Paola
Publicado: (2020)

NF-κB Members Left Home: NF-κB-Independent Roles in Cancer
por: Colomer, Carlota, et al.
Publicado: (2017)

NEMO surfaces in NF-κB–activating clusters
por: Leslie, Mitch
Publicado: (2014)

The NF-κB Activating Pathways in Multiple Myeloma
por: Roy, Payel, et al.
Publicado: (2018)

Activation of PTGS2/NF‐κB signaling pathway enhances radiation resistance of glioma
por: Tan, Cheng, et al.
Publicado: (2019)

Beyond NF-κB activation: nuclear functions of IκB kinase α
por: Huang, Wei-Chien, et al.
Publicado: (2013)

Porcine arterivirus activates the NF-κB pathway through IκB degradation
por: Lee, Sang-Myeong, et al.
Publicado: (2005)

Origin of the Functional Distinctiveness of NF-κB/p52
por: Ghosh, Gourisankar, et al.
Publicado: (2021)

Shedding Light on NF-κB Functions in Cellular Organelles
por: Carrà, Giovanna, et al.
Publicado: (2022)

New insights into the Lck-NF-κB signaling pathway
por: Zhang, Jing, et al.
Publicado: (2023)

NF-κB and the Immunoglobulin κ Gene Enhancer
por: Sen, Ranjan
Publicado: (2004)

Atypical IκB Bcl3 enhances the generation of the NF-κB p52 homodimer
por: Pan, Wenfei, et al.
Publicado: (2022)

Analysis of variation in NF-κB genes and expression levels of NF-κB-regulated molecules
por: Liu-Mares, Wen, et al.
Publicado: (2007)

Immunosuppression through constitutively activated NF-κB signalling in human ovarian cancer and its reversal by an NF-κB inhibitor
por: Nishio, H, et al.
Publicado: (2014)

What Is Nuclear Factor Kappa B (NF-κB) Doing in and to the Mitochondrion?
por: Albensi, Benedict C.
Publicado: (2019)

FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma
por: Romano, Simona, et al.
Publicado: (2015)

ZDHHC11 Positively Regulates NF-κB Activation by Enhancing TRAF6 Oligomerization
por: Liu, Enping, et al.
Publicado: (2021)

NF-κB fingerprinting reveals heterogeneous NF-κB composition in diffuse large B-cell lymphoma
por: Jayawant, Eleanor, et al.
Publicado: (2023)

Keeping NF-κB in check
por: Williams, Ruth
Publicado: (2006)

At the crossroads of SUMO and NF-κB
por: Kracklauer, Martin P, et al.
Publicado: (2003)

Slow but steady for NF-κB
por: Leslie, Mitch
Publicado: (2012)

NF-κB in premature aging
por: Osorio, Fernando G., et al.
Publicado: (2012)

Hypoxia Induced NF-κB
por: D’Ignazio, Laura, et al.
Publicado: (2016)

NF-κB signaling in inflammation
por: Liu, Ting, et al.
Publicado: (2017)

Noncanonical NF-κB in Cancer
por: Tegowski, Matthew, et al.
Publicado: (2018)

NFκB and Kidney Injury
por: Song, Ning, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ngdttfqp62safk82s0glbdq07n