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Human cytomegalovirus haplotype reconstruction reveals high diversity due to superinfection and evidence of within-host recombination

Recent sequencing efforts have led to estimates of human cytomegalovirus (HCMV) genome-wide intrahost diversity that rival those of persistent RNA viruses [Renzette N, Bhattacharjee B, Jensen JD, Gibson L, Kowalik TF (2011) PLoS Pathog 7:e1001344]. Here, we deep sequence HCMV genomes recovered from...

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Detalles Bibliográficos
Autores principales: Cudini, Juliana, Roy, Sunando, Houldcroft, Charlotte J., Bryant, Josephine M., Depledge, Daniel P., Tutill, Helena, Veys, Paul, Williams, Rachel, Worth, Austen J. J., Tamuri, Asif U., Goldstein, Richard A., Breuer, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431178/
https://www.ncbi.nlm.nih.gov/pubmed/30819890
http://dx.doi.org/10.1073/pnas.1818130116