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Motional dynamics of single Patched1 molecules in cilia are controlled by Hedgehog and cholesterol
The Hedgehog-signaling pathway is an important target in cancer research and regenerative medicine; yet, on the cellular level, many steps are still poorly understood. Extensive studies of the bulk behavior of the key proteins in the pathway established that during signal transduction they dynamical...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431229/ https://www.ncbi.nlm.nih.gov/pubmed/30819883 http://dx.doi.org/10.1073/pnas.1816747116 |