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Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients

Induced pluripotent stem cells (iPSCs) from type 1 long QT (LQT1) patients can differentiate into cardiomyocytes (CMs) including ventricular cells to recapitulate the disease phenotype. Although optical recordings using membrane potential dyes to monitor action potentials (APs) were reported, no stu...

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Detalles Bibliográficos
Autores principales: Takaki, Tadashi, Inagaki, Azusa, Chonabayashi, Kazuhisa, Inoue, Keiji, Miki, Kenji, Ohno, Seiko, Makiyama, Takeru, Horie, Minoru, Yoshida, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431403/
https://www.ncbi.nlm.nih.gov/pubmed/30956674
http://dx.doi.org/10.1155/2019/7532657