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Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients
Induced pluripotent stem cells (iPSCs) from type 1 long QT (LQT1) patients can differentiate into cardiomyocytes (CMs) including ventricular cells to recapitulate the disease phenotype. Although optical recordings using membrane potential dyes to monitor action potentials (APs) were reported, no stu...
Autores principales: | Takaki, Tadashi, Inagaki, Azusa, Chonabayashi, Kazuhisa, Inoue, Keiji, Miki, Kenji, Ohno, Seiko, Makiyama, Takeru, Horie, Minoru, Yoshida, Yoshinori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431403/ https://www.ncbi.nlm.nih.gov/pubmed/30956674 http://dx.doi.org/10.1155/2019/7532657 |
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