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Nicotinic Agonist Inhibits Cardiomyocyte Apoptosis in CVB3-Induced Myocarditis via α3β4-nAChR/PI3K/Akt-Dependent Survivin Upregulation

BACKGROUND: Cardiomyocyte apoptosis is critical for the development of coxsackievirus B3- (CVB3-) induced myocarditis, which is a common cardiac disease that may result in heart failure or even sudden death. Previous studies have associated CVB3-induced apoptosis with the downregulation of antiapopt...

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Detalles Bibliográficos
Autores principales: Li, Ping, Yan, Yaoyao, Shi, Youyang, Cheng, Bo, Zhan, Yi, Wang, Qiaoyu, Ye, Qiaofang, Weng, Yawen, Wu, Tingting, Wu, Rongzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431489/
https://www.ncbi.nlm.nih.gov/pubmed/30984342
http://dx.doi.org/10.1155/2019/9496419