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ROS Induced by KillerRed Targeting Mitochondria (mtKR) Enhances Apoptosis Caused by Radiation via Cyt c/Caspase-3 Pathway

During radiotherapy, reactive oxygen species- (ROS-) induced apoptosis is one of the main mechanism of radiation. Based on KillerRed which can induce ROS burst in different cell substructures, here we hypothesized that KillerRed targeting mitochondria (mtKR) could induce ROS to enhance apoptosis by...

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Detalles Bibliográficos
Autores principales: Li, Xin, Fang, Fang, Gao, Ying, Tang, Geng, Xu, Weiqiang, Wang, Yihan, Kong, Ruoxian, Tuyihong, Ayixianguli, Wang, Zhicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431512/
https://www.ncbi.nlm.nih.gov/pubmed/30984335
http://dx.doi.org/10.1155/2019/4528616