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Asymmetric Recruitment of β-Arrestin1/2 by the Angiotensin II Type I and Prostaglandin F2α Receptor Dimer

Initially identified as monomers, G protein-coupled receptors (GPCRs) can also form functional homo- and heterodimers that act as distinct signaling hubs for cellular signal integration. We previously found that the angiotensin II (Ang II) type 1 receptor (AT1R) and the prostaglandin F2α (PGF2α) rec...

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Detalles Bibliográficos
Autores principales: Fillion, Dany, Devost, Dominic, Sleno, Rory, Inoue, Asuka, Hébert, Terence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431625/
https://www.ncbi.nlm.nih.gov/pubmed/30936850
http://dx.doi.org/10.3389/fendo.2019.00162