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DNA Sensor IFI204 Contributes to Host Defense Against Staphylococcus aureus Infection in Mice

Interferon-inducible protein (IFI204) (p204, the murine homolog of human IFI16) is known as a cytosolic DNA sensor to recognize DNA viruses and intracellular bacteria. However, little is known about its role during extracellular bacterial infection. Here we show that IFI204 is required for host defe...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Yu, Shui-Xing, Zhou, Feng-Hua, Zhang, Xiao-Jing, Gao, Wen-Ying, Li, Kun-Yu, Liu, Zhen-Zhen, Han, Wen-Yu, Yang, Yong-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431627/
https://www.ncbi.nlm.nih.gov/pubmed/30936875
http://dx.doi.org/10.3389/fimmu.2019.00474