Mapping of Signaling Pathways Linked to sIgAD Reveals Impaired IL-21 Driven STAT3 B-Cell Activation

Objectives: It has recently been shown that individuals with selective IgA deficiency (sIgAD) have defective B cell responses both to T cell dependent and independent mimicking stimulations. The complex intracellular signaling pathways from different stimuli leading to IgA isotype switching have not...

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Detalles Bibliográficos
Autores principales: Lemarquis, Andri L., Theodors, Fannar, Einarsdottir, Helga K., Ludviksson, Bjorn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431630/
https://www.ncbi.nlm.nih.gov/pubmed/30936864
http://dx.doi.org/10.3389/fimmu.2019.00403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431630/
https://www.ncbi.nlm.nih.gov/pubmed/30936864
http://dx.doi.org/10.3389/fimmu.2019.00403

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