Prostaglanin-E2 Potentiates the Suppressive Functions of Human Mononuclear Myeloid-Derived Suppressor Cells and Increases Their Capacity to Expand IL-10-Producing Regulatory T Cell Subsets

Myeloid-derived suppressor cells (MDSC) emerged as major factors driving the tumor progression due to numerous immunosuppressive mechanisms they possess. Prostaglandin (PG)E2 is shown critical for the induction of MDSC and their suppressive functions in vivo, but it is poorly understood how it affec...

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Detalles Bibliográficos
Autores principales: Tomić, Sergej, Joksimović, Bojan, Bekić, Marina, Vasiljević, Miloš, Milanović, Marijana, Čolić, Miodrag, Vučević, Dragana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431635/
https://www.ncbi.nlm.nih.gov/pubmed/30936876
http://dx.doi.org/10.3389/fimmu.2019.00475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431635/
https://www.ncbi.nlm.nih.gov/pubmed/30936876
http://dx.doi.org/10.3389/fimmu.2019.00475

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