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Premature MicroRNA-1 Expression Causes Hypoplasia of the Cardiac Ventricular Conduction System
Mammalian cardiac Purkinje fibers (PFs) are specified from ventricular trabecular myocardium during mid-gestation and undergo limited proliferation before assuming their final form. MicroRNA-1 (miR-1), a negative regulator of proliferation, is normally expressed in the heart at low levels during the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431665/ https://www.ncbi.nlm.nih.gov/pubmed/30936836 http://dx.doi.org/10.3389/fphys.2019.00235 |