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Premature MicroRNA-1 Expression Causes Hypoplasia of the Cardiac Ventricular Conduction System

Mammalian cardiac Purkinje fibers (PFs) are specified from ventricular trabecular myocardium during mid-gestation and undergo limited proliferation before assuming their final form. MicroRNA-1 (miR-1), a negative regulator of proliferation, is normally expressed in the heart at low levels during the...

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Detalles Bibliográficos
Autores principales: Samal, Eva, Evangelista, Melissa, Galang, Giselle, Srivastava, Deepak, Zhao, Yong, Vedantham, Vasanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431665/
https://www.ncbi.nlm.nih.gov/pubmed/30936836
http://dx.doi.org/10.3389/fphys.2019.00235