OptCouple: Joint simulation of gene knockouts, insertions and medium modifications for prediction of growth-coupled strain designs

Biological production of chemicals is an attractive alternative to petrochemical-based production, due to advantages in environmental impact and the spectrum of feasible targets. However, engineering microbial strains to overproduce a compound of interest can be a long, costly and painstaking proces...

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Detalles Bibliográficos
Autores principales: Jensen, Kristian, Broeken, Valentijn, Hansen, Anne Sofie Lærke, Sonnenschein, Nikolaus, Herrgård, Markus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431744/
https://www.ncbi.nlm.nih.gov/pubmed/30956947
http://dx.doi.org/10.1016/j.mec.2019.e00087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431744/
https://www.ncbi.nlm.nih.gov/pubmed/30956947
http://dx.doi.org/10.1016/j.mec.2019.e00087

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