Cell-free DNA in the supernatant of pleural effusion can be used to detect driver and resistance mutations, and can guide tyrosine kinase inhibitor treatment decisions

OBJECTIVES: Molecular profiling of tumours has become the mainstay of diagnostics for metastasised solid malignancies and guides personalised treatment, especially in nonsmall cell lung cancer (NSCLC). In current practice, it is often challenging to obtain sufficient tumour material for reliable mol...

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Detalles Bibliográficos
Autores principales: Hummelink, Karlijn, Muller, Mirte, Linders, Theodora C., van der Noort, Vincent, Nederlof, Petra M., Baas, Paul, Burgers, Sjaak, Smit, Egbert F., Meijer, Gerrit A., van den Heuvel, Michel M., van den Broek, Daan, Monkhorst, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431750/
https://www.ncbi.nlm.nih.gov/pubmed/30918895
http://dx.doi.org/10.1183/23120541.00016-2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431750/
https://www.ncbi.nlm.nih.gov/pubmed/30918895
http://dx.doi.org/10.1183/23120541.00016-2019

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