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Co-Delivery of Imiquimod and Plasmid DNA via an Amphiphilic pH-Responsive Star Polymer that Forms Unimolecular Micelles in Water

Dual functional unimolecular micelles based on a pH-responsive amphiphilic star polymer β-CD-(PLA-b-PDMAEMA-b-PEtOxMA)(21) have been developed for the co-delivery of imiquimod and plasmid DNA to dendritic cells. The star polymer with well-defined triblock arms was synthesized by combining activator...

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Detalles Bibliográficos
Autores principales: Lin, Wenjing, Yao, Na, Li, Hongru, Hanson, Samuel, Han, Wenqing, Wang, Chun, Zhang, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431966/
https://www.ncbi.nlm.nih.gov/pubmed/30974677
http://dx.doi.org/10.3390/polym8110397