Apoptin Gene Delivery by the Functionalized Polyamidoamine (PAMAM) Dendrimer Modified with Ornithine Induces Cell Death of HepG2 Cells

The use of tumor-specific therapeutic agents is a promising option for efficient and safe nonviral gene transfer in gene therapy. In this study, we describe the efficacy of polyamidoamine (PAMAM)-based nonviral gene delivery carriers, namely, an ornithine conjugated PAMAM (PAMAM-O) dendrimer in deli...

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Detalles Bibliográficos
Autores principales: Bae, Yoonhee, Song, Su Jeong, Mun, Ji Young, Ko, Kyung Soo, Han, Jin, Choi, Joon Sig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432117/
https://www.ncbi.nlm.nih.gov/pubmed/30970874
http://dx.doi.org/10.3390/polym9060197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432117/
https://www.ncbi.nlm.nih.gov/pubmed/30970874
http://dx.doi.org/10.3390/polym9060197

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