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Development of Poly(ɛ-Caprolactone) Scaffold Loaded with Simvastatin and Beta-Cyclodextrin Modified Hydroxyapatite Inclusion Complex for Bone Tissue Engineering

In this study, we developed poly(ɛ-caprolactone) (PCL) 3D scaffolds using a solid free form fabrication (SFF) technique. β-cyclodextrin (βCD) was grafted to hydroxyapatite (HAp) and this βCD grafted HAp was coated onto the PCL scaffold surface, followed by drug loading through an inclusion complex i...

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Detalles Bibliográficos
Autores principales: Lee, Jung Bok, Kim, Ji Eun, Bae, Min Soo, Park, Su A, Balikov, Daniel A., Sung, Hak-joon, Jeon, Hoon Bong, Park, Hun Kuk, Um, Soong Ho, Lee, Kook Sun, Kwon, Il Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432564/
https://www.ncbi.nlm.nih.gov/pubmed/30979140
http://dx.doi.org/10.3390/polym8020049