Optimizing a CRISPR-Cpf1-based genome engineering system for Corynebacterium glutamicum

BACKGROUND: Corynebacterium glutamicum is an important industrial strain for the production of a diverse range of chemicals. Cpf1 nucleases are highly specific and programmable, with efficiencies comparable to those of Cas9. Although the Francisella novicida (Fn) CRISPR-Cpf1 system has been adapted...

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Detalles Bibliográficos
Autores principales: Zhang, Jiao, Yang, Fayu, Yang, Yunpeng, Jiang, Yu, Huo, Yi-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432761/
https://www.ncbi.nlm.nih.gov/pubmed/30909908
http://dx.doi.org/10.1186/s12934-019-1109-x

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