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RNase H1 promotes replication fork progression through oppositely transcribed regions of Drosophila mitochondrial DNA

Mitochondrial DNA (mtDNA) replication uses a simple core machinery similar to those of bacterial viruses and plasmids, but its components are challenging to unravel. Here, we found that, as in mammals, the single Drosophila gene for RNase H1 (rnh1) has alternative translational start sites, resultin...

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Detalles Bibliográficos
Autores principales: González de Cózar, Jose M., Gerards, Mike, Teeri, Eveliina, George, Jack, Dufour, Eric, Jacobs, Howard T., Jõers, Priit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433063/
https://www.ncbi.nlm.nih.gov/pubmed/30635398
http://dx.doi.org/10.1074/jbc.RA118.007015