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pH-sensitive doxorubicin-loaded polymeric nanocomplex based on β-cyclodextrin for liver cancer-targeted therapy

BACKGROUND: Doxorubicin (DOX) is one of the most effective treatments for hepatocellular carcinoma (HCC), but is restricted by its poor pharmacokinetics. Herein, we exploited efficient targeted drug delivery systems and they have been found to be a worthy strategy for liver cancer therapy. MATERIALS...

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Detalles Bibliográficos
Autores principales: Yang, Tianfeng, Du, Guowen, Cui, Yuxin, Yu, Runze, Hua, Chen, Tian, Wei, Zhang, Yanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433111/
https://www.ncbi.nlm.nih.gov/pubmed/30962684
http://dx.doi.org/10.2147/IJN.S193170