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Suppressed OGT expression inhibits cell proliferation and modulates EGFR expression in renal cell carcinoma

PURPOSE: O-linked N-acetylglucosamine (O-GlcNAc or O-GlcNAcylation) is a post-translational modification, which plays a vital role in the progression of various cancers. The purpose of the present study was to assess O-GlcNAcylation in human renal cell carcinoma (RCC). METHODS: O-GlcNAcylation level...

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Detalles Bibliográficos
Autores principales: Wang, Longsheng, Chen, Shaojun, Zhang, Junfeng, Mao, Shiyu, Mao, Weipu, Zhang, Wentao, Guo, Yadong, Wu, Yuan, Wang, Ruiliang, Yan, Yang, Yao, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433112/
https://www.ncbi.nlm.nih.gov/pubmed/30962710
http://dx.doi.org/10.2147/CMAR.S190642