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Sensitive high-throughput single-cell RNA-Seq reveals within-clonal transcript-correlations in yeast populations

Single-cell RNA-seq has revealed extensive cellular heterogeneity within many organisms, but few methods have been developed for microbial clonal populations. The yeast genome displays unusually dense transcript spacing, with interleaved and overlapping transcription from both strands, resulting in...

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Detalles Bibliográficos
Autores principales: Nadal-Ribelles, Mariona, Islam, Saiful, Wei, Wu, Latorre, Pablo, Nguyen, Michelle, de Nadal, Eulàlia, Posas, Francesc, Steinmetz, Lars M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433287/
https://www.ncbi.nlm.nih.gov/pubmed/30718850
http://dx.doi.org/10.1038/s41564-018-0346-9