Phosphatidylinositol 3‐kinase pathway genomic alterations in 60,991 diverse solid tumors informs targeted therapy opportunities

BACKGROUND: The phosphatidylinositol 3‐kinase (PI3K) pathway is frequently altered in cancer. This report describes the landscape of PI3K alterations in solid tumors as well as co‐alterations serving as potential resistance/attenuation mechanisms. METHODS: Consecutive samples were analyzed in a comm...

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Detalles Bibliográficos
Autores principales: Millis, Sherri Z., Jardim, Denis L., Albacker, Lee, Ross, Jeffrey S., Miller, Vincent A., Ali, Siraj M., Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433468/
https://www.ncbi.nlm.nih.gov/pubmed/30582752
http://dx.doi.org/10.1002/cncr.31921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433468/
https://www.ncbi.nlm.nih.gov/pubmed/30582752
http://dx.doi.org/10.1002/cncr.31921

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