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Sustained exposure to prostaglandin D(2) augments the contraction induced by acetylcholine via a DP(1) receptor-mediated activation of p38 in bronchial smooth muscle of naive mice
Prostaglandin D(2) (PGD(2)), one of the key lipid mediators of allergic airway inflammation, is increased in the airways of asthmatics. However, the role of PGD(2) in the pathogenesis of asthma is not fully understood. In the present study, effects of PGD(2) on smooth muscle contractility of the air...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Japan Society of Smooth Muscle Research
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433600/ https://www.ncbi.nlm.nih.gov/pubmed/30918168 http://dx.doi.org/10.1540/jsmr.55.1 |