Chondroprotection of PPARα activation by WY14643 via autophagy involving Akt and ERK in LPS‐treated mouse chondrocytes and osteoarthritis model

Autophagy maintains cellular homoeostasis. The enhancement of autophagy in chondrocytes could prevent osteoarthritis (OA) progression in articular cartilage. Peroxisome proliferator‐activated receptor α (PPARα) activation may also protect articular chondrocytes against cartilage degradation in OA. H...

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Detalles Bibliográficos
Autores principales: Zhou, Yang, Chen, Xiaolei, Qu, Ning, Zhang, Bing, Xia, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433667/
https://www.ncbi.nlm.nih.gov/pubmed/30729704
http://dx.doi.org/10.1111/jcmm.14184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433667/
https://www.ncbi.nlm.nih.gov/pubmed/30729704
http://dx.doi.org/10.1111/jcmm.14184

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