Trans‐3,5,4´‐trimethoxystilbene reduced gefitinib resistance in NSCLCs via suppressing MAPK/Akt/Bcl‐2 pathway by upregulation of miR‐345 and miR‐498

Despite initial dramatic efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR‐TKIs) in EGFR‐mutant lung cancer patients, subsequent emergence of acquired resistance is almost inevitable. Resveratrol and its derivatives have been found to exert some effects on EGFR‐TKI...

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Detalles Bibliográficos
Autores principales: Lu, Min, Liu, Bin, Xiong, Hui, Wu, Fang, Hu, Chunhong, Liu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433677/
https://www.ncbi.nlm.nih.gov/pubmed/30701693
http://dx.doi.org/10.1111/jcmm.14086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433677/
https://www.ncbi.nlm.nih.gov/pubmed/30701693
http://dx.doi.org/10.1111/jcmm.14086

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