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Down‐regulation of miR‐200c attenuates AngII‐induced cardiac hypertrophy via targeting the MLCK‐mediated pathway

BACKGROUND: MicroRNAs (miRNAs) have been shown to commonly contribute to cardiac hypertrophy (CH). The aim of this study was to test the hypothesis that miR‐200c plays an important role in the progression of CH by targeting myosin light chain kinase (MLCK/MYLK). METHODS AND RESULTS: Cardiac hypertro...

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Detalles Bibliográficos
Autores principales: Hu, Shan, Cheng, Mian, Guo, Xin, Wang, Shun, Liu, Beilei, Jiang, Hong, Huang, Congxin, Wu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433679/
https://www.ncbi.nlm.nih.gov/pubmed/30680929
http://dx.doi.org/10.1111/jcmm.14135