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Fibroblast growth factor 16 stimulates proliferation but blocks differentiation of rat stem Leydig cells during regeneration

OBJECTIVES: We aim to investigate the effects of fibroblast growth factor 16 (FGF16) on Leydig cell regeneration in ethane dimethane sulphonate (EDS)‐treated rat testis. METHODS: We intraperitoneally inject 75 mg/kg EDS to adult male Sprague Dawley rats and then intratesticularly inject FGF16 (0, 10...

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Detalles Bibliográficos
Autores principales: Duan, Yue, Wang, Yiyan, Li, Xiaoheng, Mo, Jiaying, Guo, Xiaoling, Li, Chao, Tu, Mengyan, Ge, Fei, Zheng, Wenwen, Lin, Jing, Ge, Ren‐Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433688/
https://www.ncbi.nlm.nih.gov/pubmed/30672118
http://dx.doi.org/10.1111/jcmm.14157