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Polymorphism in Cytochrome P450 3A4 Is Ethnicity Related

Can mutations in Cytochrome P450 3A4 (CYP3A4), the major food- and drug-metabolizing enzyme, serve as biomarkers for personalized precise medicine? Classical genetic studies provide only limited data regarding the frequencies of CYP3A4 mutations and their role in food–drug interactions. Here, in an...

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Detalles Bibliográficos
Autores principales: Guttman, Yelena, Nudel, Adi, Kerem, Zohar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433705/
https://www.ncbi.nlm.nih.gov/pubmed/30941162
http://dx.doi.org/10.3389/fgene.2019.00224