Type 2 diabetes is associated with suppression of autophagy and lipid accumulation in β‐cells

Both type 2 diabetes (T2D) and obesity are characterized by excessive hyperlipidaemia and subsequent lipid droplet (LD) accumulation in adipose tissue. To investigate whether LDs also accumulate in β‐cells of T2D patients, we assessed the expression of PLIN2, a LD‐associated protein, in non‐diabetic...

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Detalles Bibliográficos
Autores principales: Ji, Jeff, Petropavlovskaia, Maria, Khatchadourian, Armen, Patapas, Jason, Makhlin, Julia, Rosenberg, Lawrence, Maysinger, Dusica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433726/
https://www.ncbi.nlm.nih.gov/pubmed/30710421
http://dx.doi.org/10.1111/jcmm.14172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433726/
https://www.ncbi.nlm.nih.gov/pubmed/30710421
http://dx.doi.org/10.1111/jcmm.14172

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