An integrative systems approach identifies novel candidates in Marfan syndrome‐related pathophysiology

Marfan syndrome (MFS) is an autosomal dominant genetic disorder caused by mutations in the FBN1 gene. Although many peripheral tissues are affected, aortic complications, such as dilation, dissection and rupture, are the leading causes of MFS‐related mortality. Aberrant TGF‐beta signalling plays a m...

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Detalles Bibliográficos
Autores principales: Bhushan, Raghu, Altinbas, Lukas, Jäger, Marten, Zaradzki, Marcin, Lehmann, Daniel, Timmermann, Bernd, Clayton, Nicholas P., Zhu, Yunxiang, Kallenbach, Klaus, Kararigas, Georgios, Robinson, Peter N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433740/
https://www.ncbi.nlm.nih.gov/pubmed/30677223
http://dx.doi.org/10.1111/jcmm.14137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433740/
https://www.ncbi.nlm.nih.gov/pubmed/30677223
http://dx.doi.org/10.1111/jcmm.14137

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