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Plant Extracts and Phytochemicals Targeting α-Synuclein Aggregation in Parkinson's Disease Models

α-Synuclein (α-syn) is a presynaptic protein that regulates the release of neurotransmitters from synaptic vesicles in the brain. α-Syn aggregates, including Lewy bodies, are features of both sporadic and familial forms of Parkinson's disease (PD). These aggregates undergo several key stages of...

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Detalles Bibliográficos
Autores principales: Javed, Hayate, Nagoor Meeran, Mohamed Fizur, Azimullah, Sheikh, Adem, Abdu, Sadek, Bassem, Ojha, Shreesh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433754/
https://www.ncbi.nlm.nih.gov/pubmed/30941047
http://dx.doi.org/10.3389/fphar.2018.01555