Impaired Redox Signaling in Huntington’s Disease: Therapeutic Implications

Huntington’s disease (HD) is a neurodegenerative disease triggered by expansion of polyglutamine repeats in the protein huntingtin. Mutant huntingtin (mHtt) aggregates and elicits toxicity by multiple mechanisms which range from dysregulated transcription to disturbances in several metabolic pathway...

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Detalles Bibliográficos
Autores principales: Paul, Bindu D., Snyder, Solomon H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433839/
https://www.ncbi.nlm.nih.gov/pubmed/30941013
http://dx.doi.org/10.3389/fnmol.2019.00068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433839/
https://www.ncbi.nlm.nih.gov/pubmed/30941013
http://dx.doi.org/10.3389/fnmol.2019.00068

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