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EIF5A regulates proliferation and chemoresistance in pancreatic cancer through the sHH signalling pathway

BACKGROUND: Pancreatic cancer (PC) has a very poor prognosis and comparatively short survival. Eukaryotic translation initiation factor 5A (EIF5A) promotes cancer metastasis. Here, we exploited the biological role of EIF5A in PC chemoresistance. METHODS: Expression of EIF5A was analysed in PC cells...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Jiang, Jie, Qin, Tao, Xiao, Ying, Han, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433860/
https://www.ncbi.nlm.nih.gov/pubmed/30761741
http://dx.doi.org/10.1111/jcmm.14167