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Tanycyte-Independent Control of Hypothalamic Leptin Signaling

Leptin is secreted by adipocytes to regulate appetite and body weight. Recent studies have reported that tanycytes actively transport circulating leptin across the brain barrier into the hypothalamus, and are required for normal levels of hypothalamic leptin signaling. However, direct evidence for l...

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Detalles Bibliográficos
Autores principales: Yoo, Sooyeon, Cha, David, Kim, Dong Won, Hoang, Thanh V., Blackshaw, Seth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433882/
https://www.ncbi.nlm.nih.gov/pubmed/30941008
http://dx.doi.org/10.3389/fnins.2019.00240