Cargando…

Differential Targeting of c-Maf, Bach-1, and Elmo-1 by microRNA-143 and microRNA-365 Promotes the Intracellular Growth of Mycobacterium tuberculosis in Alternatively IL-4/IL-13 Activated Macrophages

Mycobacterium tuberculosis (Mtb) can subvert the host defense by skewing macrophage activation toward a less microbicidal alternative activated state to avoid classical effector killing functions. Investigating the molecular basis of this evasion mechanism could uncover potential candidates for host...

Descripción completa

Detalles Bibliográficos
Autores principales: Tamgue, Ousman, Gcanga, Lorna, Ozturk, Mumin, Whitehead, Lauren, Pillay, Shandre, Jacobs, Raygaana, Roy, Sugata, Schmeier, Sebastian, Davids, Malika, Medvedeva, Yulia A., Dheda, Keertan, Suzuki, Harukazu, Brombacher, Frank, Guler, Reto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433885/
https://www.ncbi.nlm.nih.gov/pubmed/30941122
http://dx.doi.org/10.3389/fimmu.2019.00421