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Differential Targeting of c-Maf, Bach-1, and Elmo-1 by microRNA-143 and microRNA-365 Promotes the Intracellular Growth of Mycobacterium tuberculosis in Alternatively IL-4/IL-13 Activated Macrophages
Mycobacterium tuberculosis (Mtb) can subvert the host defense by skewing macrophage activation toward a less microbicidal alternative activated state to avoid classical effector killing functions. Investigating the molecular basis of this evasion mechanism could uncover potential candidates for host...
Autores principales: | Tamgue, Ousman, Gcanga, Lorna, Ozturk, Mumin, Whitehead, Lauren, Pillay, Shandre, Jacobs, Raygaana, Roy, Sugata, Schmeier, Sebastian, Davids, Malika, Medvedeva, Yulia A., Dheda, Keertan, Suzuki, Harukazu, Brombacher, Frank, Guler, Reto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433885/ https://www.ncbi.nlm.nih.gov/pubmed/30941122 http://dx.doi.org/10.3389/fimmu.2019.00421 |
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