Generation of a Fully Human scFv that binds Tumor-Specific Glycoforms

Tumor-specific glycosylation changes are an attractive target for the development of diagnostic and therapeutic applications. Periostin is a glycoprotein with high expression in many tumors of epithelial origin including ovarian cancer. Strategies to target the peptide portion of periostin as a diag...

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Detalles Bibliográficos
Autores principales: Lu, Zhongpeng, Kamat, Kalika, Johnson, Blake P., Yin, Catherin C., Scholler, Nathalie, Abbott, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433917/
https://www.ncbi.nlm.nih.gov/pubmed/30911061
http://dx.doi.org/10.1038/s41598-019-41567-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433917/
https://www.ncbi.nlm.nih.gov/pubmed/30911061
http://dx.doi.org/10.1038/s41598-019-41567-6

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