Cargando…
Building Potent Chimeric Antigen Receptor T Cells With CRISPR Genome Editing
Chimeric antigen receptor (CAR) T cells have shown great promise in the treatment of hematological and solid malignancies. However, despite the success of this field, there remain some major challenges, including accelerated T cell exhaustion, potential toxicities, and insertional oncogenesis. To ov...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433930/ https://www.ncbi.nlm.nih.gov/pubmed/30941126 http://dx.doi.org/10.3389/fimmu.2019.00456 |