Preclinical Evaluation of Bispecific Adaptor Molecule Controlled Folate Receptor CAR-T Cell Therapy With Special Focus on Pediatric Malignancies

Chimeric antigen receptor (CAR)-T cell therapy has transformed pediatric oncology by producing high remission rates and potent effects in CD19+ B-cell malignancies. This scenario is ideal as CD19 expression is homogeneous and human blood provides a favorable environment for CAR-T cells to thrive and...

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Detalles Bibliográficos
Autores principales: Lu, Yingjuan J., Chu, Haiyan, Wheeler, Leroy W., Nelson, Melissa, Westrick, Elaine, Matthaei, James F., Cardle, Ian I., Johnson, Adam, Gustafson, Joshua, Parker, Nikki, Vetzel, Marilynn, Xu, Le-Cun, Wang, Emilia Z., Jensen, Michael C., Klein, Patrick J., Low, Philip S., Leamon, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433934/
https://www.ncbi.nlm.nih.gov/pubmed/30941303
http://dx.doi.org/10.3389/fonc.2019.00151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433934/
https://www.ncbi.nlm.nih.gov/pubmed/30941303
http://dx.doi.org/10.3389/fonc.2019.00151

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