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Therapeutic Targeting of Cancer Stem Cells: Integrating and Exploiting the Acidic Niche
Cancer stem cells (CSC) or tumor-initiating cells represent a small subpopulation of cells within the tumor bulk that share features with somatic stem cells, such as self-renewal and pluripotency. From a clinical point of view, CSC are thought to be the main drivers of tumor relapse in patients by s...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433943/ https://www.ncbi.nlm.nih.gov/pubmed/30941310 http://dx.doi.org/10.3389/fonc.2019.00159 |