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A Pathogenic Role for Splenic B1 Cells in SIV Disease Progression in Rhesus Macaques

B1 cells spontaneously produce protective natural antibodies which provide the first line of defense against a variety of pathogens. Although these natural antibodies share similar autoreactive features with several HIV-1 broadly neutralizing antibodies, the role of B1 cells in HIV/SIV disease progr...

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Detalles Bibliográficos
Autores principales: Enyindah-Asonye, Gospel, Nwankwo, Anthony, Hogge, Christopher, Rahman, Mohammad Arif, Helmold Hait, Sabrina, Hunegnaw, Ruth, Ko, Eun-Ju, Hoang, Tanya, Venzon, David J., Robert-Guroff, Marjorie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433970/
https://www.ncbi.nlm.nih.gov/pubmed/30941141
http://dx.doi.org/10.3389/fimmu.2019.00511