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A Pathogenic Role for Splenic B1 Cells in SIV Disease Progression in Rhesus Macaques
B1 cells spontaneously produce protective natural antibodies which provide the first line of defense against a variety of pathogens. Although these natural antibodies share similar autoreactive features with several HIV-1 broadly neutralizing antibodies, the role of B1 cells in HIV/SIV disease progr...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433970/ https://www.ncbi.nlm.nih.gov/pubmed/30941141 http://dx.doi.org/10.3389/fimmu.2019.00511 |