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ZEB1 protects skeletal muscle from damage and is required for its regeneration

The mechanisms linking muscle injury and regeneration are not fully understood. Here we report an unexpected role for ZEB1 regulating inflammatory and repair responses in dystrophic and acutely injured muscles. ZEB1 is upregulated in the undamaged and regenerating myofibers of injured muscles. Compa...

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Detalles Bibliográficos
Autores principales: Siles, Laura, Ninfali, Chiara, Cortés, Marlies, Darling, Douglas S., Postigo, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434033/
https://www.ncbi.nlm.nih.gov/pubmed/30910999
http://dx.doi.org/10.1038/s41467-019-08983-8