Bone marrow central memory and memory stem T-cell exhaustion in AML patients relapsing after HSCT

The major cause of death after allogeneic Hematopoietic Stem Cell Transplantation (HSCT) for acute myeloid leukemia (AML) is disease relapse. We investigated the expression of Inhibitory Receptors (IR; PD-1/CTLA-4/TIM-3/LAG-3/2B4/KLRG1/GITR) on T cells infiltrating the bone marrow (BM) of 32 AML pat...

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Detalles Bibliográficos
Autores principales: Noviello, Maddalena, Manfredi, Francesco, Ruggiero, Eliana, Perini, Tommaso, Oliveira, Giacomo, Cortesi, Filippo, De Simone, Pantaleo, Toffalori, Cristina, Gambacorta, Valentina, Greco, Raffaella, Peccatori, Jacopo, Casucci, Monica, Casorati, Giulia, Dellabona, Paolo, Onozawa, Masahiro, Teshima, Takanori, Griffioen, Marieke, Halkes, Constantijn J. M., Falkenburg, J. H. F., Stölzel, Friedrich, Altmann, Heidi, Bornhäuser, Martin, Waterhouse, Miguel, Zeiser, Robert, Finke, Jürgen, Cieri, Nicoletta, Bondanza, Attilio, Vago, Luca, Ciceri, Fabio, Bonini, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434052/
https://www.ncbi.nlm.nih.gov/pubmed/30911002
http://dx.doi.org/10.1038/s41467-019-08871-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434052/
https://www.ncbi.nlm.nih.gov/pubmed/30911002
http://dx.doi.org/10.1038/s41467-019-08871-1

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