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Changes of Bax, Bcl-2, CCR-2, MCP-1, and TGF-β1 genes in the left ventricle of spontaneously hypertensive rat after losartan treatment

PURPOSE: Increased apoptosis was recently found in the hypertrophied left ventricle of spontaneously hypertensive rats (SHRs). Although the available evidence suggests that apoptosis can be induced in cardiac cells by various insults including pressure overload, cardiac apoptosis appears to result f...

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Detalles Bibliográficos
Autores principales: Lee, Hyeryon, Kim, Kwan Chang, Hong, Young Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Pediatric Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434229/
https://www.ncbi.nlm.nih.gov/pubmed/30360036
http://dx.doi.org/10.3345/kjp.2018.06856