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The HDAC Inhibitor, SAHA, Combined with Cisplatin Synergistically Induces Apoptosis in Alpha-fetoprotein-producing Hepatoid Adenocarcinoma Cells

Hepatoid adenocarcinoma (HAC) is a rare and aggressive gastrointestinal tract cancer that is characterized by hepatic differentiation and production of alpha-fetoprotein (AFP). Cisplatin is mainly used to treat HAC, but the efficacy is poor. Recently, the histone deacetylase inhibitor, suberoylanili...

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Detalles Bibliográficos
Autores principales: Kyaw, Myat Tin Htwe, Yamaguchi, Yuya, Choijookhuu, Narantsog, Yano, Koichi, Takagi, Hideaki, Takahashi, Nobuyasu, Synn Oo, Phyu, Sato, Katsuaki, Hishikawa, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434315/
https://www.ncbi.nlm.nih.gov/pubmed/30923410
http://dx.doi.org/10.1267/ahc.18044