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Apc gene suppresses intracranial aneurysm formation and rupture through inhibiting the NF-κB signaling pathway mediated inflammatory response

Background: Intracranial aneurysm (IA) is a critical acquired cerebrovascular disease that may cause subarachnoid hemorrhage, and nuclear factor-κB (NF-κB)-mediated inflammation is involved in the pathogenesis of IA. Adenomatous polyposis coli (Apc) gene is a tumor suppressor gene associated with bo...

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Detalles Bibliográficos
Autores principales: Lai, Xian-Liang, Deng, Zhi-Feng, Zhu, Xin-Gen, Chen, Zhi-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434386/
https://www.ncbi.nlm.nih.gov/pubmed/30808715
http://dx.doi.org/10.1042/BSR20181909